Polynucleotides (Salmon DNA Treatment)

Polynucleotides are advanced injectable skin regeneration treatments designed to improve skin quality at a cellular level. They are derived from highly purified DNA fragments and support tissue repair, hydration, and cellular renewal. In aesthetic medicine, polynucleotides are sometimes informally referred to as “salmon DNA” treatments, reflecting their biological origin, while clinically they are regulated and used as medical polynucleotide-based injectables.

At our clinic in Lisbon, Portugal, polynucleotide treatments are offered as part of a regenerative, longevity-focused approach to skin rejuvenation. Rather than adding volume or altering facial contours, polynucleotides enhance the skin’s natural repair mechanisms, resulting in healthier, more resilient, and more radiant skin over time.

 

What Polynucleotides Do

  • Stimulate fibroblast activity and collagen production
  • Support cellular regeneration and tissue repair
  • Improve microcirculation and tissue quality
  • Enhance skin hydration, elasticity, and resilience

 

Who Are Polynucleotide Treatments Suitable For

Polynucleotide treatments are suitable for women and men of all ages who wish to improve skin quality in a natural and regenerative way. They are particularly beneficial for:

  • Early signs of skin aging
  • Dehydrated, dull, or stressed skin
  • Reduced skin elasticity and firmness
  • Skin affected by environmental damage or oxidative stress

They are also ideal for patients seeking regenerative anti-aging treatments in Lisbon without
volumizing effects.

Treatment Areas

  • Face
  • Neck
  • Décolletage
  • Hands
  • Periocular area (when clinically appropriate)

Treatment Protocol

  • Usually performed as a series of 2 to 3 treatment sessions
  • Sessions are spaced 2 to 4 weeks apart
  • Minimally invasive procedure performed in a medical outpatient setting

Are Polynucleotides Safe?

Yes, polynucleotides are biodegradable and biocompatible, as they are composed of natural molecular building blocks. This ensures excellent tolerability and minimizes the risk of side effects when treatments are performed by experienced medical professionals.

Results and Longevity

  • Gradual, natural improvement in skin quality and resilience
  • Results typically last 6 to 9 months, depending on skin condition and lifestyle
  • Maintenance treatments may be recommended to support long-term skin health

Downtime and Safety

  • Minimal to no downtime
  • Temporary redness, mild swelling, or small injection marks may occur
  • High safety profile when administered by trained medical professionals

Combination Treatments

Polynucleotides can be safely combined with:

  • Botulinum toxin
  • Hyaluronic acid treatments
  • Skinboosters
  • Biostimulatory treatments such as Sculptra® or Radiesse®

Polynucleotides, also known as salmon DNA skin treatments, are an excellent option for patients seeking advanced regenerative skin rejuvenation in Lisbon, with a strong focus on skin health, repair, and long-term anti-aging results.